BMS-806 (BMS 378806)
目录号: A11201
HIV Entry 抑制剂
BMS-806,也被称为 BMS-378806,是一种被称为进入抑制剂的药物。进入抑制剂通过阻止HIV进入人体细胞来发挥作用。BMS-378806(BMS-806)是一种小分子,它阻断宿主细胞CD4与病毒gp120蛋白的结合,从而抑制HIV-1感染的最初步骤。
Discription | BMS-806, also known as BMS-378806 , is a type of medicine called an entry inhibitor. Entry inhibitors work by blocking HIV from entering human cells. BMS-378806 (BMS-806) is a small molecule that blocks the binding of host-cell CD4 with viral gp120 protein and therefore inhibits the first steps of HIV-1 infection. | |||||
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Cell Research |
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目录号 | A11201 |
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分子式 | C22H22N4O4 |
分子量 | 406.43 |
CAS号 | 357263-13-9 |
SMILES | C[C@@H]1CN(CCN1C(=O)C(=O)C2=CNC3=NC=CC(=C23)OC)C(=O)C4=CC=CC=C4 |
其他名称 | BMS806, BMS378806, BMS-378806 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 73 mg/mL (179.61 mM) | |
Water | Insoluble | ||
Ethanol | 3 mg/mL (7.38 mM) | ||
In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.6 mL | 123.02 mL | 246.04 mL |
0.5 mM | 4.92 mL | 24.6 mL | 49.21 mL |
1 mM | 2.46 mL | 12.3 mL | 24.6 mL |
5 mM | 0.49 mL | 2.46 mL | 4.92 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2