BMS-806 (BMS 378806)

Name: BMS-806 (BMS 378806)
SKU: A11201

目录号: A11201

HIV Entry 抑制剂

BMS-806 (BMS 378806) Chemical Structure

CAS NO. 357263-13-9

BMS-806，也称为BMS-378806，选择性抑制HIV-1 gp120与CD4受体结合，EC50为0.85-26.5 nM。通过阻止HIV进入人体细胞而发挥作用。可阻断宿主细胞CD4与病毒gp120蛋白的结合，因此可抑制HIV-1感染的第一步。

库存：现货

规格	价格	数量
5 mg	￥ 630.00
10 mg	￥ 1,120.00
50 mg	￥ 3,360.00
100 mg	￥ 6,160.00
10mM * 1mL in DMSO	￥ 924.00

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产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

溶解度 *

In vitro (25°C)	DMSO	73 mg/mL (179.61 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (7.38 mM)
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.6 mL	123.02 mL	246.04 mL
0.5 mM	4.92 mL	24.6 mL	49.21 mL
1 mM	2.46 mL	12.3 mL	24.6 mL
5 mM	0.49 mL	2.46 mL	4.92 mL

*The above data is based on the productmolecular weight 406.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11201
作用机制	Inhibitor (抑制剂)
M. Wt	406.43
Formula	C22H22N4O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	357263-13-9
Synonyms	BMS806, BMS378806, BMS-378806
SMILES	C[C@@H]1CN(CCN1C(=O)C(=O)C2=CNC3=NC=CC(=C23)OC)C(=O)C4=CC=CC=C4