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BMS-819881 is a melaninconcentrating hormone receptor 1 (MCHR1) antagonist, which binds rat MCHR1 with a Ki of 7 nM. BMS-819881 also is selective and potent for CYP3A4 activity with an EC50 of 13 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.32 mL | 106.62 mL | 213.24 mL |
| 0.5 mM | 4.26 mL | 21.32 mL | 42.65 mL |
| 1 mM | 2.13 mL | 10.66 mL | 21.32 mL |
| 5 mM | 0.43 mL | 2.13 mL | 4.26 mL |
*The above data is based on the productmolecular weight 468.95. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21500 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 468.95 |
| Formula | C24H21ClN2O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1197420-05-5 |
| Synonyms | BMS 819881; BMS819881 |
| SMILES | ClC1=CC=C(C2=CC(N=CN(C3=CC(OC)=C(OC[C@H](O)C4CC4)C=C3)C5=O)=C5S2)C=C1 |
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