BMS-986165

目录号: A18726

TYK2 抑制剂

BMS-986165

BMS-986165 Chemical Structure

CAS NO. 1609392-27-9

BMS-986165 is a Highly Potent and Selective Allosteric Inhibitor of TYK2. BMS-986165 Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bowel Disease.

库存: 现货

规格 价格 数量
2 mg
¥ 1,750.00
5 mg
¥ 3,640.00
10 mg
¥ 5,600.00
50 mg
¥ 17,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

BMS-986165 is a Highly Potent and Selective Allosteric Inhibitor of TYK2. BMS-986165 Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bowel Disease.
In vitro DMSO 27 mg/mL (63.46 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.5 mL 117.52 mL 235.04 mL
0.5 mM 4.7 mL 23.5 mL 47.01 mL
1 mM 2.35 mL 11.75 mL 23.5 mL
5 mM 0.47 mL 2.35 mL 4.7 mL

*The above data is based on the productmolecular weight 425.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A18726
作用机制 Inhibitor (抑制剂)
M. Wt 425.46
Formula C20H19D3N8O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1609392-27-9
Synonyms BMS-986165; BMS 986165; BMS986165;
SMILES O=C(C1=NN=C(NC(C2CC2)=O)C=C1NC3=CC=CC(C4=NN(C)C=N4)=C3OC)NC([2H])([2H])[2H]

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