Deucravacitinib (BMS-986165)

Name: Deucravacitinib (BMS-986165)
SKU: A18726
Price: 385 CNY
Rating: 5 (288 reviews)

目录号: A18726

TYK2 抑制剂

BMS-986165 是一种高效且选择性的 TYK2 配体抑制剂。BMS-986165 阻断 Il-12、IL-23 和 type I Interferon 信号传导，并在炎症性肠病的临床前模型中显示出强大的疗效。

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Grouped product items
规格	价格	库存
1mg	¥385.00	现货
2mg	¥595.00	现货
5mg	¥1,050.00	现货
10mg	¥1,960.00	现货
25mg	¥3,150.00	现货
50mg	¥4,655.00	现货
100mg	¥6,650.00	现货
200mg	¥8,995.00	现货
500mg	¥13,405.00	现货
*10mM 1mL in DMSO**	¥1,120.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

BMS-986165 is a Highly Potent and Selective Allosteric Inhibitor of TYK2. BMS-986165 Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bowel Disease.

Targets

Target	Value

产品信息

目录号	A18726
分子式	C20H19D3N8O3
分子量	425.46
CAS号	1609392-27-9
SMILES	O=C(C1=NN=C(NC(C2CC2)=O)C=C1NC3=CC=CC(C4=NN(C)C=N4)=C3OC)NC([2H])([2H])[2H]
其他名称	BMS-986165; BMS 986165; BMS986165;
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	27 mg/mL (63.46 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.5 mL	117.52 mL	235.04 mL
0.5 mM	4.7 mL	23.5 mL	47.01 mL
1 mM	2.35 mL	11.75 mL	23.5 mL
5 mM	0.47 mL	2.35 mL	4.7 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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