BMS-986205
目录号: A17013
IDO1 抑制剂
BMS-986205,亦称为 Linrodostat、ONO-7701 及 F001287,是一种强效且选择性的口服 IDO1 抑制剂,具有潜在的免疫调节和抗肿瘤活性。CAS 号:1923833-60-6(自由基) 2221034-29-1(甲磺酸盐)
Discription | BMS-986205, also known as Linrodostat, ONO-7701 and F001287, a potent and selective, orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities. CAS: 1923833-60-6 (free base) 2221034-29-1 (mesylate) | |||||
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Cell Research |
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目录号 | A17013 |
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分子式 | C24H24ClFN2O |
分子量 | 410.91 |
CAS号 | 1923833-60-6 |
SMILES | C[C@H]([C@H]1CC[C@@H](C2=CC=NC3=CC=C(F)C=C23)CC1)C(NC4=CC=C(Cl)C=C4)=O |
其他名称 | BMS 986205, BMS986205, ONO-7701; ONO 7701, ONO7701, F-001287, F001287, F001287, Linrodostat |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 74 mg/mL (180.08 mM) | |
Water | Insoluble | ||
Ethanol | 74 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.34 mL | 121.68 mL | 243.36 mL |
0.5 mM | 4.87 mL | 24.34 mL | 48.67 mL |
1 mM | 2.43 mL | 12.17 mL | 24.34 mL |
5 mM | 0.49 mL | 2.43 mL | 4.87 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2