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BMT-145027 is an mGluR5 positive allosteric modulator without inherent agonist activity, exhibits an EC50 of 47 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.79 mL | 113.94 mL | 227.88 mL |
| 0.5 mM | 4.56 mL | 22.79 mL | 45.58 mL |
| 1 mM | 2.28 mL | 11.39 mL | 22.79 mL |
| 5 mM | 0.46 mL | 2.28 mL | 4.56 mL |
*The above data is based on the productmolecular weight 438.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12457 |
|---|---|
| 作用机制 | Modulator (调节剂) |
| M. Wt | 438.83 |
| Formula | C23H14ClF3N4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2018282-44-3 |
| Synonyms | BMT145027, BMT 145027 |
| SMILES | ClC(C(C(F)(F)F)=C1)=CC=C1C2=NNC3=NC(C4=CC=CC=C4)=C(C#N)C(C5CC5)=C32 |
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