Bortezomib (Velcade)

Name: Bortezomib (Velcade)
SKU: A10160

目录号: A10160

Proteasome 抑制剂

Product Citations (13)

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Bortezomib (Velcade) Chemical Structure

CAS NO. 179324-69-7

Bortezomib (Velcade)是26S蛋白酶体的高度选择性，可逆抑制剂。

库存：现货

规格	价格	数量
5 mg	￥ 210.00
10 mg	￥ 406.00
25 mg	￥ 686.00
100 mg	￥ 1,120.00
10mM * 1mL in DMSO	￥ 350.00

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产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

Bortezomib (Velcade)是26S蛋白酶体的高度选择性，可逆抑制剂。

靶点信息

20S proteasome (Cell-free assay)
0.6 nM(Ki)

溶解度 *

In vitro (25°C)	DMSO	66 mg/mL (171.77 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.03 mL	130.14 mL	260.28 mL
0.5 mM	5.21 mL	26.03 mL	52.06 mL
1 mM	2.6 mL	13.01 mL	26.03 mL
5 mM	0.52 mL	2.6 mL	5.21 mL

*The above data is based on the productmolecular weight 384.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10160
作用机制	Inhibitor (抑制剂)
M. Wt	384.2
Formula	C19H25BN4O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	179324-69-7
Synonyms	MG-341, PS-341
SMILES	B([C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O