Bozitinib

Name: Bozitinib
SKU: A18554
Price: 700 CNY
Rating: 5 (288 reviews)

目录号: A18554

c-MET kinase 抑制剂

Bozitinib (PLB-1001) 是一种高度选择性的 c-MET 激酶抑制剂，具有血脑屏障渗透性。Bozitinib (PLB-1001) 是一种与酪氨酸激酶超家族的传统 ATP-结合口袋 结合的 ATP-竞争性小分子抑制剂。

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Grouped product items
规格	价格	库存
1mg	¥700.00	现货
5mg	¥1,540.00	现货
10mg	¥2,555.00	现货
25mg	¥4,585.00	现货
50mg	¥6,615.00	现货
100mg	¥9,275.00	现货
*10mM 1mL in DMSO**	¥1,715.00	现货
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Data Sheet

SDS

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生物活性

Discription	Bozitinib (PLB-1001) is a highly selective c-MET kinase inhibitor with blood-brain barrier permeability. Bozitinib (PLB-1001) is a ATP-competitive small-molecule inhibitor, binds to the conventional ATP-binding pocket of the tyrosine kinase superfamily.

产品信息

目录号	A18554
分子式	C20H15F3N8
分子量	424.38
CAS号	1440964-89-5
SMILES	CN1N=C2C=C(F)C(C(C3=NN=C4C=CC(C5=CN(C6CC6)N=C5)=NN43)(F)F)=CC2=C1
其他名称	PLB-1001, PLB1001, PLB 1001
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	79 mg/mL (186.15 mM)
	Water	Insoluble
	Ethanol	2 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.56 mL	117.82 mL	235.64 mL
0.5 mM	4.71 mL	23.56 mL	47.13 mL
1 mM	2.36 mL	11.78 mL	23.56 mL
5 mM	0.47 mL	2.36 mL	4.71 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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