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Branaplam

Branaplam

Name: Branaplam
SKU: A20714

目录号: A20714

SMN2 splicing modulator

Branaplam Chemical Structure

CAS NO. 1562338-42-4

Branaplam (LMI070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.

库存：现货

规格	价格	数量
5 mg	￥ 756.00
10 mg	￥ 1,302.00
50 mg	￥ 3,864.00
100 mg	￥ 7,728.00

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生物活性

Branaplam (LMI070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.

溶解度 *

In vitro	DMSO	3 mg/mL (7.62 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.41 mL	127.07 mL	254.14 mL
0.5 mM	5.08 mL	25.41 mL	50.83 mL
1 mM	2.54 mL	12.71 mL	25.41 mL
5 mM	0.51 mL	2.54 mL	5.08 mL

*The above data is based on the productmolecular weight 393.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20714
M. Wt	393.48
Formula	C22H27N5O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1562338-42-4
Synonyms	LMI070, LMI 070, LMI-070; NVS-SM1
SMILES	OC1=CC(C2=CNN=C2)=CC=C1C3=CC=C(OC4CC(C)(C)NC(C)(C)C4)N=N3