BRCA1-IN-2
目录号: A20464
PPI inhibitor
BRCA1-IN-2(化合物15)是一种细胞渗透性的蛋白-蛋白相互作用(PPI)抑制剂,针对BRCA1,具有 IC50 为0.31 μM和 Kd 为0.3 μM,通过破坏BRCA1 (BRCT)2/蛋白相互作用显示出抗肿瘤活性。
Discription | BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT)2/protein interactions. |
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目录号 | A20464 |
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分子式 | C26H33N4O7P |
分子量 | 544.54 |
CAS号 | 1622262-55-8 |
SMILES | O=C(N[C@@H](COP(O)(O)=O)C(NCC(NCCCCC1=CC=CC=C1)=O)=O)CCC2=CNC3=C2C=CC=C3 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2