BRD7-IN-1 free base
目录号: A21530
BRD7-IN-1 free base 是 BI7273(BRD7/9 抑制剂)的改良衍生物,通过连接体与 VHL 配体结合,形成 PROTAC VZ185(针对 BRD7/9 的 VZ185,其 DC50 分别为 4.5 和 1.8 nM)。
Discription | BRD7-IN-1 free base, a modified derivative of BI7273 (BRD7/9 inhibitor), binds to a VHL ligand via a linker to form a PROTAC VZ185 (VZ185 against BRD7/9 with DC50s of 4.5 and 1.8 nM, respectively). |
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目录号 | A21530 |
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分子式 | C22H26N4O3 |
分子量 | 394.47 |
CAS号 | 2305379-66-0 |
SMILES | CN1C=C(C2=CC(OC)=C(CN3CCNCC3)C(OC)=C2)C(C=CN=C4)=C4C1=O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2