微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
Brivanib alaninate (BMS-582664)是VEGFR和FGFR信号转导的双重酪氨酸激酶抑制剂。
靶点信息
| VEGFR2 | Flk1 | FGFR1 | VEGFR1 | |
| 25 nM | 89 nM | 148 nM | 380 nM |
| In vitro (25°C) | DMSO | 83 mg/mL (188 mM) | |
| Water | Insoluble | ||
| Ethanol | 83 mg/mL (188 mM) | ||
| In vivo | 0.5% methylcellulose+0.2% Tween 80 | 9 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.65 mL | 113.25 mL | 226.5 mL |
| 0.5 mM | 4.53 mL | 22.65 mL | 45.3 mL |
| 1 mM | 2.27 mL | 11.33 mL | 22.65 mL |
| 5 mM | 0.45 mL | 2.27 mL | 4.53 mL |
*The above data is based on the productmolecular weight 441.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10162 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 441.5 |
| Formula | C22H24FN5O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 649735-63-7 |
| Synonyms | BMS582664 |
| SMILES | CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[C@@H](C)OC(=O)[C@H](C)N)C |
产品资料
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Vatalanib (PTK787) 2HCl
Vatalanib (PTK787) 2HCl是一种小分子蛋白激酶抑制剂，可抑制抑制所有已知VEGF受体以及血小板衍生的生长因子…
(-)-Catechin gallate
(-)-Catechin gallate是绿茶的抗氧化成分。在uM浓度下，抑制VEGF诱导的酪氨酸磷酸化。
Cediranib (AZD2171)
Cediranib (AZD2171)是一种高效的VEGFR(KDR)抑制剂，此外对c-Kit和PDGFRβ也具有相似的抑制活性，对VEGFR的选择性比P…
CYC116 (CYC-116)
CYC116 (CYC-116)是一种有效的Aurora A/B抑制剂，Ki为8.0 nM/9.2 nM，对VEGFR2(Ki为44 nM)作用稍弱。
Linifanib (ABT-869)
Linifanib (ABT-869)是一种结构新颖的有效RTK，VEGF和PDGF抑制剂，对人内皮细胞，PDGFR-β，KDR和CSF-1R的IC50分别为0.…
ZM 323881 hydrochloride
ZM 323881 hydrochloride是一种有效且选择性的人血管内皮生长因子受体2（VEGFR2/KDR）激酶活性抑制剂。
BMS-817378
BMS-817378是Met/VEGFR-2双重抑制剂BMS-794833的新型前药。
Keywords:购买 Brivanib alaninate (BMS-582664) | Brivanib alaninate (BMS-582664) 供应商 | 订购 Brivanib alaninate (BMS-582664) | Brivanib alaninate (BMS-582664) 价格 | Brivanib alaninate (BMS-582664) 生产商 | 订单 Brivanib alaninate (BMS-582664) | Brivanib alaninate (BMS-582664) 代理商 | 购买 649735-63-7| 649735-63-7 供应商 | 订购 649735-63-7 | 649735-63-7 价格 | 649735-63-7 生产商 | 订单 649735-63-7 | 649735-63-7 代理商|buy Brivanib alaninate (BMS-582664) | Brivanib alaninate (BMS-582664) Supplier | purchase Brivanib alaninate (BMS-582664) | Brivanib alaninate (BMS-582664) cost | Brivanib alaninate (BMS-582664) manufacturer | order Brivanib alaninate (BMS-582664) | Brivanib alaninate (BMS-582664) distributor | buy 649735-63-7| 649735-63-7 Supplier | purchase 649735-63-7 | 649735-63-7 cost | 649735-63-7 manufacturer | order 649735-63-7 | 649735-63-7 distributor