你的浏览器似乎禁用了 JavaScript。
您必须在浏览器中启用JavaScript才能使用本网站的功能。

微信关注
申请试用装

主页 /
Protein Tyrosine Kinases /
FGFR /
Brivanib (BMS-540215)

Brivanib (BMS-540215)

目录号: A10254

VEGFR-2 抑制剂

Product Citations (1)

Brivanib (BMS-540215) Chemical Structure

CAS NO. 649735-46-6

Brivanib (BMS-540215)是一种VEGFR-2抑制剂，IC50为25 nM，Ki为26 nM。

库存：现货

规格	价格	数量
5 mg	￥ 630.00
10 mg	￥ 1,120.00
50 mg	￥ 3,150.00
200 mg	￥ 8,400.00
10mM * 1mL in DMSO	￥ 882.00

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

顾客使用 Adooq 产品发表的高质量科研文献

产品详情

生物活性

Brivanib (BMS-540215)是一种VEGFR-2抑制剂，IC50为25 nM，Ki为26 nM。

Targets

Target	Value
VEGFR2	IC50: 25nM
Flk1	IC50: 89nM
FGFR1	IC50: 148nM
VEGFR1	IC50: 380nM
EGFR	IC50: >1.9μM
LCK	IC50: >2.5μM
PDGFRβ	IC50: >6μM
PKCα	IC50: >25μM
JAK3	IC50: >50μM

溶解度 *

In vitro	DMSO	71 mg/mL (191.69 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (8.09 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27 mL	134.99 mL	269.98 mL
0.5 mM	5.4 mL	27 mL	54 mL
1 mM	2.7 mL	13.5 mL	27 mL
5 mM	0.54 mL	2.7 mL	5.4 mL

*The above data is based on the productmolecular weight 370.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10254
作用机制	Inhibitor (抑制剂)
M. Wt	370.4
Formula	C19H19FN4O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	649735-46-6
Synonyms	BMS540215
SMILES	CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[C@@H](C)O)C

产品资料

Download Brivanib (BMS-540215) SD file

Products Specification Data Sheet

Safety Data Sheet (SDS)

产品标签

产品标签

使用空格分隔标签。使用单引号（'）标注词组。

Product Questions

Product Questions

No Questions

您还可能对下列产品感兴趣

SKLB1002

SKLB1002是一种新型的有效VEGFR2抑制剂，可显着抑制HUVEC增殖，迁移，侵袭和管形成。

添加到收藏

Quick View 添加并比较

RAF265 (CHIR-265)

RAF265 (CHIR-265)是一种口服，高度选择性的RAF和VEGFR激酶抑制剂，可控制或正常化VEGFR-2，同时抑制B-raf和c-Raf�…

添加到收藏

Quick View 添加并比较

E7080 (Lenvatinib)

E7080 (Lenvatinib)是一种多激酶抑制剂，可同时抑制VEGFR2和VEGFR3激酶。

添加到收藏

Quick View 添加并比较

ZM 306416

ZM 306416 hydrochloride是一种VEGF受体酪氨酸激酶抑制剂，可抑制KDR（IC50 = 100 nM）和Flt（IC50 = 2 uM）酪氨酸激酶�…

添加到收藏

Quick View 添加并比较

NVP-BAW2881

NVP-BAW2881是有效的选择性VEGFR抑制剂（血管内皮生长因子受体酪氨酸激酶抑制剂），IC50 为值9 nM，具有抑制�…

添加到收藏

Quick View 添加并比较

XL647 (Tesevatinib)

XL647 (Tesevatinib)是一种口服生物可利用的小分子RTK抑制剂，可结合并抑制在肿瘤细胞增殖和肿瘤血管形成中�…

添加到收藏

Quick View 添加并比较

Toceranib (PHA 291639, SU 11654)

Toceranib (PHA 291639,SU 11654)是一种激酶抑制剂，通过抑制KIT，血管内皮生长因子受体2和PDGFRβ同时具有抗肿瘤�…

添加到收藏

Quick View 添加并比较

XL184 free base (Cabozantinib)

XL184 free base (Cabozantinib)是设计用来抑制多种受体酪氨酸激酶（特别是MET和VEGFR2）的小分子。

添加到收藏

Quick View 添加并比较

Keywords:购买 Brivanib (BMS-540215) | Brivanib (BMS-540215) 供应商 | 订购 Brivanib (BMS-540215) | Brivanib (BMS-540215) 价格 | Brivanib (BMS-540215) 生产商 | 订单 Brivanib (BMS-540215) | Brivanib (BMS-540215) 代理商 | 购买 649735-46-6| 649735-46-6 供应商 | 订购 649735-46-6 | 649735-46-6 价格 | 649735-46-6 生产商 | 订单 649735-46-6 | 649735-46-6 代理商|buy Brivanib (BMS-540215) | Brivanib (BMS-540215) Supplier | purchase Brivanib (BMS-540215) | Brivanib (BMS-540215) cost | Brivanib (BMS-540215) manufacturer | order Brivanib (BMS-540215) | Brivanib (BMS-540215) distributor | buy 649735-46-6| 649735-46-6 Supplier | purchase 649735-46-6 | 649735-46-6 cost | 649735-46-6 manufacturer | order 649735-46-6 | 649735-46-6 distributor

联系我们

Not your Region? View all Distributors

溶液配制计算器

分子量计算器

稀释计算器

摩尔浓度计算器

ADOOQ 产品质量保证

Guaranteed product quality, 365 days Unconditional Return & Replacement

We promise all products to perform as described.