目录号: A11178
5-HT1D receptor 拮抗剂
BRL-15572 是一种选择性的 h5-HT1D 拮抗剂,相对于 h5-HT1B 显示出60倍的选择性,并且对其他多种受体类型几乎没有或完全没有亲和力。
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生物活性
Discription | BRL-15572 is a selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B, and exhibiting little or no affinity for a range of other receptor types. |
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Targets |
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产品信息
目录号 | A11178 |
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分子式 | C25H29Cl3N2O |
分子量 | 479.87 |
CAS号 | 193611-72-2 |
SMILES | C1CN(CCN1CC(C(C2=CC=CC=C2)C3=CC=CC=C3)O)C4=CC(=CC=C4)Cl.Cl.Cl |
其他名称 | BRL15572, BRL 15572 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
In vitro (25°C) | DMSO | 89 mg/mL (185.46 mM) | |
Water | Insoluble | ||
Ethanol | 37 mg/mL (77.1 mM) | ||
In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 19 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Preparing Stock Solutions
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.84 mL | 104.19 mL | 208.39 mL |
0.5 mM | 4.17 mL | 20.84 mL | 41.68 mL |
1 mM | 2.08 mL | 10.42 mL | 20.84 mL |
5 mM | 0.42 mL | 2.08 mL | 4.17 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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