Bromosporine
目录号: A13163
bromodomain 抑制剂
Bromosporine 是一种广谱的 bromodomains 抑制剂,其 IC50 分别为 BRD2 的 0.41 μM、BRD4 的 0.29 μM、BRD9 的 0.122 μM 和 CECR2 的 0.017 μM。
Discription | Bromosporine is a broad spectrum inhibitor for bromodomains with IC50 of 0.41 μM, 0.29 μM, 0.122 μM and 0.017 μM for BRD2, BRD4, BRD9 and CECR2, respectively. |
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目录号 | A13163 |
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分子式 | C17H20N6O4S |
分子量 | 404.44 |
CAS号 | 1619994-69-2 |
SMILES | CCOC(=O)NC1=CC(=NN2C1=NN=C2C)C3=CC(=C(C=C3)C)NS(=O)(=O)C |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 77 mg/mL (190.38 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.73 mL | 123.63 mL | 247.26 mL |
0.5 mM | 4.95 mL | 24.73 mL | 49.45 mL |
1 mM | 2.47 mL | 12.36 mL | 24.73 mL |
5 mM | 0.49 mL | 2.47 mL | 4.95 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2