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Bryostatin 1是从海洋苔藓动物Bugula neritina分离的大内酯，可调节蛋白激酶C（PKC）活性。 Bryostain 1诱导了PKC的初始快速活化和自磷酸化，从而导致PKC酶向膜的移位。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 11.05 mL | 55.25 mL | 110.49 mL |
| 0.5 mM | 2.21 mL | 11.05 mL | 22.1 mL |
| 1 mM | 1.1 mL | 5.52 mL | 11.05 mL |
| 5 mM | 0.22 mL | 1.1 mL | 2.21 mL |
*The above data is based on the productmolecular weight 905.03. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10261 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 905.03 |
| Formula | C47H68O17 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 83314-01-6 |
| Synonyms | NSC 339555 |
| SMILES | CCC/C=C/C=C/C(=O)O[C@H]1/C(=C/C(=O)OC)/C[C@H]2C[C@@H](OC(=O)C[C@@H](C[C@@H]3C[C@@H](C([C@@](O3)(C[C@@H]4C/C(=C/C(=O)OC)/C[C@@H](O4)/C=C/C([C@@]1(O2)O)(C)C)O)(C)C)OC(=O)C)O)[C@@H](C)O |
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