BTZ043 (BTZ038, BTZ044) Racemate
目录号: A10165
DprE1 抑制剂
BTZ043(BTZ038,BTZ044)抑制了去十戍烯基磷酸-β-D-核糖 2?-差向异构酶,这是一种产生致病细菌结核分枝杆菌细胞壁的酶。
Discription | BTZ043 (BTZ038, BTZ044) inhibits decaprenylphosphoryl-β-d-ribose 2?-epimerase, which is an enzyme which produces the cell wall of the pathogenic bacterium Mycobacterium tuberculosis. | |||||
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Cell Research |
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目录号 | A10165 |
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分子式 | C17H16F3N3O5S |
分子量 | 431.4 |
CAS号 | 957217-65-1 |
SMILES | CC1COC2(O1)CCN(CC2)C3=NC(=O)C4=CC(=CC(=C4S3)[N+](=O)[O-])C(F)(F)F |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 21 mg/mL (48.67 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 0.5% CMC | 14 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.18 mL | 115.9 mL | 231.8 mL |
0.5 mM | 4.64 mL | 23.18 mL | 46.36 mL |
1 mM | 2.32 mL | 11.59 mL | 23.18 mL |
5 mM | 0.46 mL | 2.32 mL | 4.64 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2