C-178
目录号: A19049
STING 抑制剂
C-178，一种与Cys91结合的共价STING抑制剂，能够强效且选择性地抑制由不同真正激活剂引发的小鼠STING反应，但对人类无效。
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生物活性
| Discription | C-178, a covalent inhibitor of STING, binds to Cys91, potently and selectively suppresses the STING responses elicited by distinct bona fide activators in mouse but not human. |
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产品信息
| 目录号 | A19049 |
|---|---|
| 分子式 | C17H10N2O5 |
| 分子量 | 322.27 |
| CAS号 | 329198-87-0 |
| SMILES | O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C3C(OC4=CC=CC=C34)=C2 |
| 其他名称 | C178; C 178 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 28 mg/mL (86.88 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.03 mL | 155.15 mL | 310.3 mL |
| 0.5 mM | 6.21 mL | 31.03 mL | 62.06 mL |
| 1 mM | 3.1 mL | 15.51 mL | 31.03 mL |
| 5 mM | 0.62 mL | 3.1 mL | 6.21 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 329198-87-0 | 329198-87-0 供应商 | 329198-87-0 花费 | 329198-87-0 生产商 | 订购 329198-87-0 | 329198-87-0 代理商