c-di-AMP
目录号: A21823
STING 激动剂
c-di-AMP(环二腺苷酸)是一种 STING 激动剂,它通过结合跨膜蛋白 STING 来激活 TBK3-IRF3 信号通路,随后触发 I型 IFN 和 TNF 的产生。
Discription | c-di-AMP (Cyclic diadenylate) is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. |
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目录号 | A21823 |
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分子式 | C20H24N10O12P2 |
分子量 | 658.41 |
CAS号 | 54447-84-6 |
SMILES | O[C@H]([C@@](OP(O)(OC[C@](O[C@@H](N1C2=NC=NC(N)=C2N=C1)[C@@H]3O)([H])[C@@]3([H])O4)=O)([H])[C@](COP4(O)=O)([H])O5)[C@@H]5N6C7=NC=NC(N)=C7N=C6 |
其他名称 | Cyclic diadenylate; Cyclic-di-AMP |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2