C25-140

目录号: A18705
TRAF6-Ubc13 inhibitor
C25-140,一种首创的、相对选择性的 TRAF6-Ubc13 抑制剂,直接与 TRAF6 结合,并阻断 TRAF6Ubc13 的相互作用。C25-140 降低 TRAF6 活性,减少 NF-κB 激活,并对抗自身免疫性疾病。
Grouped product items
规格 价格 库存 数量
1mg
¥420.00
现货
5mg
¥980.00
现货
10mg
¥1,330.00
现货
25mg
¥2,835.00
现货
50mg
¥4,690.00
现货
100mg
¥6,615.00
现货
10mM * 1mL in DMSO
¥980.00
现货
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生物活性
Discription C25-140, a first-in-class, fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reduces NF-κB activation, and combats autoimmunity.
产品信息
目录号 A18705
分子式 C26H31N7O
分子量 457.57
CAS号 1358099-18-9
SMILES O=C(N1CCC(CC2=CC=CC=C2)CC1)CCC3=C(C)N(C4=NN5C(C=C4)=NN=C5C)N=C3C
其他名称 C25140; C-25140; C 25140; C25 140; C25-140; C-25-140;
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 89 mg/mL (194.5 mM)
Water Insoluble
Ethanol 89 mg/mL (194.5 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.85 mL 109.27 mL 218.55 mL
0.5 mM 4.37 mL 21.85 mL 43.71 mL
1 mM 2.19 mL 10.93 mL 21.85 mL
5 mM 0.44 mL 2.19 mL 4.37 mL
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