C25-140
目录号: A18705
TRAF6-Ubc13 inhibitor
C25-140,一种首创的、相对选择性的 TRAF6-Ubc13 抑制剂,直接与 TRAF6 结合,并阻断 TRAF6 与 Ubc13 的相互作用。C25-140 降低 TRAF6 活性,减少 NF-κB 激活,并对抗自身免疫性疾病。
Discription | C25-140, a first-in-class, fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reduces NF-κB activation, and combats autoimmunity. |
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目录号 | A18705 |
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分子式 | C26H31N7O |
分子量 | 457.57 |
CAS号 | 1358099-18-9 |
SMILES | O=C(N1CCC(CC2=CC=CC=C2)CC1)CCC3=C(C)N(C4=NN5C(C=C4)=NN=C5C)N=C3C |
其他名称 | C25140; C-25140; C 25140; C25 140; C25-140; C-25-140; |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 89 mg/mL (194.5 mM) | |
Water | Insoluble | ||
Ethanol | 89 mg/mL (194.5 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.85 mL | 109.27 mL | 218.55 mL |
0.5 mM | 4.37 mL | 21.85 mL | 43.71 mL |
1 mM | 2.19 mL | 10.93 mL | 21.85 mL |
5 mM | 0.44 mL | 2.19 mL | 4.37 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2