CA-074 Methyl Ester
CA-074 甲酯是 CA-074 的一种细胞渗透性类似物，作为不可逆的组织蛋白酶 B 抑制剂。CA-074 甲酯被报道在啮齿动物模型中抑制骨吸收，并且已显示在体外抑制 B16 黑色素瘤细胞的侵袭。
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Adooq用户使用CA-074 Methyl Ester发表的4篇文献
生物活性
| Discription | CA-074 methyl ester is a cell-permeable analog of CA-074 that acts as an irreversible cathepsin B inhibitor. CA-074 methyl ester is reported to inhibit bone resorption in rodent models and shown to inhibit B16 melanoma cell invasion in vitro. |
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产品信息
| 目录号 | A13593 |
|---|---|
| 分子式 | C19H31N3O6 |
| 分子量 | 397.5 |
| CAS号 | 147859-80-1 |
| SMILES | CCCNC(=O)C1C(O1)C(=O)NC(C(C)CC)C(=O)N2CCCC2C(=O)OC |
| 其他名称 | CA-074 Me |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 77 mg/mL (193.72 mM) | |
| Water | 77 mg/mL (193.72 mM) | ||
| Ethanol | 6 mg/mL (15.09 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.16 mL | 125.79 mL | 251.57 mL |
| 0.5 mM | 5.03 mL | 25.16 mL | 50.31 mL |
| 1 mM | 2.52 mL | 12.58 mL | 25.16 mL |
| 5 mM | 0.5 mL | 2.52 mL | 5.03 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 147859-80-1 | 147859-80-1 供应商 | 147859-80-1 花费 | 147859-80-1 生产商 | 订购 147859-80-1 | 147859-80-1 代理商