Cabazitaxel

Name: Cabazitaxel
SKU: A11831

目录号: A11831

Microtubule Associated 抑制剂

Product Citations (2)

Cabazitaxel Chemical Structure

CAS NO. 183133-96-2

Cabazitaxel是一种天然紫杉烷的半合成衍生物。Cabazitaxel联合泼尼松是基于多西他赛的激素难治性前列腺癌的治疗选择。

库存：现货

规格	价格	数量
50 mg	￥ 560.00
100 mg	￥ 1,190.00
250 mg	￥ 2,100.00
10mM * 1mL in DMSO	￥ 504.00

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产品详情

生物活性

Cabazitaxel是一种天然紫杉烷的半合成衍生物。Cabazitaxel联合泼尼松是基于多西他赛的激素难治性前列腺癌的治疗选择。

靶点信息

Microtubule (Cell-free assay)

溶解度 *

In vitro	DMSO	91 mg/mL (108.85 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	11.96 mL	59.81 mL	119.63 mL
0.5 mM	2.39 mL	11.96 mL	23.93 mL
1 mM	1.2 mL	5.98 mL	11.96 mL
5 mM	0.24 mL	1.2 mL	2.39 mL

*The above data is based on the productmolecular weight 835.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11831
作用机制	Inhibitor (抑制剂)
M. Wt	835.93
Formula	C45H57NO14
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	183133-96-2
Synonyms	TXD-258, XRP 6258
SMILES	CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC