CAL-101 (GS-1101, Idelalisib)

Name: CAL-101 (GS-1101, Idelalisib)
SKU: A10172
Price: 175 CNY
Rating: 5 (5 reviews)

目录号: A10172

PI3K 抑制剂

5 篇发表文献

CAL-101 是一种选择性抑制 PI3K 的异构体抑制剂，能够诱导慢性淋巴细胞性白血病（CLL）细胞的凋亡。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥245.00	现货
25mg	¥420.00	现货
50mg	¥560.00	现货
100mg	¥735.00	现货
200mg	¥945.00	现货
500mg	¥1,610.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用CAL-101 (GS-1101, Idelalisib)发表的5篇文献

Kevin J Pridham, .et al. , iScience, 2024, May 7;27(6):109921 PMID: 38812542

Ming-Chun Hung, .et al. , Cell Biosci, 2022, 12: 122 PMID: 35918763

Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168

Pridham KJ, .et al. , Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844

Yoshihiro Umezawa, .et al. , J Biol Chem, 2017, Dec 1; 292(48): 19639-19655 PMID: 28974577

生物活性

Discription

CAL-101 is an isoform-selective inhibitor of PI3K that induces apoptosis of chronic lymphocytic leukemia (CLL) cells.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10172
分子式	C22H18FN7O
分子量	415.4
CAS号	870281-82-6
SMILES	CC[C@@H](C1=NC2=C(C(=CC=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 76 mg/mL (182.94 mM)
	Water	Insoluble
	Ethanol	21 mg/mL (50.55 mM)
In vivo	2% DMSO+20%PEG 300+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.07 mL	120.37 mL	240.73 mL
0.5 mM	4.81 mL	24.07 mL	48.15 mL
1 mM	2.41 mL	12.04 mL	24.07 mL
5 mM	0.48 mL	2.41 mL	4.81 mL

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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