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Canertinib (CI-1033)

目录号: A10211
HER2/ErbB2 抑制剂
Canertinib (CI-1033) 是一种不可逆的酪氨酸激酶抑制剂,对 EGFR (IC50 0.8 nM)、HER-2 (IC50 19 nM) 和 ErbB-4 (IC50 7 nM) 有活性。
Grouped product items
规格 价格 库存 数量
5mg
¥175.00
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10mg
¥315.00
现货
25mg
¥385.00
现货
50mg
¥490.00
现货
100mg
¥945.00
现货
200mg
¥1,435.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

Other Forms of Canertinib (CI-1033)

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Canertinib (CI-1033)发表的1篇文献
  • Fukuda N, .et al. , ACS Synth Biol., 2015, 4(4):421-9 PMID: 25006755
  • 生物活性
    Discription Canertinib (CI-1033) is an irreversible tyrosine-kinase inhibitor with activity against EGFR (IC50 0.8 nM), HER-2 (IC50 19 nM) and ErbB-4 (IC50 7 nM).
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A10211
    分子式 C24H25ClFN5O3
    分子量 485.9
    CAS号 267243-28-7
    SMILES C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
    其他名称 PD-183805
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 2 mg/mL (4.11 mM)
    Water Insoluble
    Ethanol 8 mg/mL (16.46 mM)
    In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.58 mL 102.9 mL 205.8 mL
    0.5 mM 4.12 mL 20.58 mL 41.16 mL
    1 mM 2.06 mL 10.29 mL 20.58 mL
    5 mM 0.41 mL 2.06 mL 4.12 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

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