Capecitabine (Xeloda)

Name: Capecitabine (Xeloda)
SKU: A10177
Price: 210 CNY
Rating: 5 (4 reviews)

目录号: A10177

4 篇发表文献

Capecitabine 是一种前体药物，它在肿瘤中通过酶的作用转化为5-氟尿嘧啶，从而抑制 DNA 合成并减缓肿瘤组织的生长。Capecitabine 的激活遵循一个包含三个酶促步骤和两个中间代谢物，5'-脱氧-5-氟胞苷（5'-DFCR）和5'-脱氧-5-氟尿苷（5'-DFUR），最终形成5-氟尿嘧啶的路径。

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Grouped product items
规格	价格	库存
500mg	¥210.00	现货
1g	¥245.00	现货
5g	¥1,085.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Capecitabine (Xeloda)发表的4篇文献

Majid Momeny, .et al. , EMBO Mol Med, 2024, Jun 17 PMID: 38886591

Takashi Azuma, .et al. , SEP PURIF TECHNOL, 2019, Apr; 212: 483-489

Azuma T, .et al. , Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504

Azuma T, .et al. , Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347

生物活性

Discription

Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouridine (5'-DFUR), to form 5-fluorouracil.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10177
分子式	C15H22FN3O6
分子量	359.4
CAS号	154361-50-9
SMILES	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@H]2[C@@H]([C@@H]([C@H](O2)C)O)O
其他名称	Captabin
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	62 mg/mL (172.53 mM)
	Water	5 mg/mL (13.91 mM)
	Ethanol	62 mg/mL (172.53 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.82 mL	139.12 mL	278.24 mL
0.5 mM	5.56 mL	27.82 mL	55.65 mL
1 mM	2.78 mL	13.91 mL	27.82 mL
5 mM	0.56 mL	2.78 mL	5.56 mL

Useful Calculator

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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