Capsazepine
目录号: A21208
TRPV1 receptor antagonist
Capsazepine 是一种感觉神经元兴奋毒素的合成类似物，是 TRPV1 受体 的拮抗剂，其 IC50 为 562 nM。
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生物活性
| Discription | Capsazepine is a synthetic analogue of the sensory neurone excitotoxin, and an antagonist of TRPV1 receptor with an IC50 of 562 nM. | |||||
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| Cell Research |
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产品信息
| 目录号 | A21208 |
|---|---|
| 分子式 | C19H21ClN2O2S |
| 分子量 | 376.9 |
| CAS号 | 138977-28-3 |
| SMILES | S=C(N1CCCC2=CC(O)=C(O)C=C2C1)NCCC3=CC=C(Cl)C=C3 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 68 mg/mL (180.42 mM) | |
| Water | Insoluble | ||
| Ethanol | 68 mg/mL (180.42 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.53 mL | 132.66 mL | 265.32 mL |
| 0.5 mM | 5.31 mL | 26.53 mL | 53.06 mL |
| 1 mM | 2.65 mL | 13.27 mL | 26.53 mL |
| 5 mM | 0.53 mL | 2.65 mL | 5.31 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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