Carglumic Acid

Name: Carglumic Acid
SKU: A17588
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A17588

CPS1 activator

卡格鲁酸（N-羧甲基-L-谷氨酸），是N-乙酰谷氨酸（NAG）的功能类似物和羧酰磷酸合成酶1（CPS1）的激活剂，用于治疗与NAG合成酶（NAGS）缺乏症相关的急性和慢性高氨血症。

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Grouped product items
规格	价格	库存
200mg	¥280.00	现货
250mg	¥315.00	现货
500mg	¥560.00	现货
1g	¥770.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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Data Sheet

SDS

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生物活性

Discription	Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.

产品信息

目录号	A17588
分子式	C6H10N2O5
分子量	190.15
CAS号	1188-38-1
SMILES	O=C(O)[C@@H](NC(N)=O)CCC(O)=O
其他名称	OE312, OE-312, OE 312, AJ 266447, AJ-26647, AJ26647; Carglumic Acid.
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	34 mg/mL (178.8 mM)
	Ethanol	<1 mg/mL
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	52.59 mL	262.95 mL	525.9 mL
0.5 mM	10.52 mL	52.59 mL	105.18 mL
1 mM	5.26 mL	26.3 mL	52.59 mL
5 mM	1.05 mL	5.26 mL	10.52 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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