Cariprazine hydrochloride

目录号: A15036
D3/D2 Dopamine Receptor Antagonist
Cariprazine hydrochloride 是一种新型抗精神病药物候选物,具有高选择性和亲和力,对多巴胺 D3 (Ki=0.09 nM) 和 D2 (Ki=0.5 nM) 受体表现出高亲和力,对血清素 5-HT(1A) 受体则表现出中等亲和力。
Grouped product items
规格 价格 库存 数量
5mg
¥175.00
现货
10mg
¥280.00
现货
25mg
¥490.00
现货
50mg
¥770.00
现货
100mg
¥1,155.00
现货
500mg
¥2,940.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription Cariprazine hydrochloride is a novel antipsychotic drug candidate that exhibits high selectivity and affinity to dopamine D3(Ki=0.09 nM) and D2 (Ki=0.5 nM) receptors and moderate affinity to serotonin 5-HT(1A) receptors.
Targets
Target Value
产品信息
目录号 A15036
分子式 C21H33Cl3N4O
分子量 463.87
CAS号 1083076-69-0
SMILES CN(C)C(=O)NC1CCC(CC1)CCN2CCN(CC2)C3=C(C(=CC=C3)Cl)Cl.Cl
其他名称 RGH-188 hydrochloride, RGH 188 hydrochloride, RGH188 hydrochloride
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 4 mg/mL (8.62 mM)
Water 3 mg/mL (6.46 mM)
Ethanol 3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.56 mL 107.79 mL 215.58 mL
0.5 mM 4.31 mL 21.56 mL 43.12 mL
1 mM 2.16 mL 10.78 mL 21.56 mL
5 mM 0.43 mL 2.16 mL 4.31 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

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