Caspase
Catalog No. | Inhibitor Name | Pan-Caspase | Caspase-1 | Caspase-2 | Caspase-3 | Caspase-4 | Caspase-5 | Caspase-6 | Caspase-7 | Caspase-8 | Caspase-9 | Caspase-10 |
---|---|---|---|---|---|---|---|---|---|---|---|---|
A10984 | VX-765 (Belnacasan) | ** | *** | |||||||||
A12373 | Z-VAD-FMK | * | ||||||||||
A13503 | Z-DEVD-FMK | |||||||||||
A14915 | Q-VD-OPh hydrate | **** | **** | *** | *** | |||||||
A14919 | Caspase-3/7 Inhibitor I | **** | *** | |||||||||
A12611 | Z-VEID-FMK | |||||||||||
A12637 | Z-VDVAD-FMK | |||||||||||
A12697 | Z-DQMD-FMK | |||||||||||
A12800 | Z-IETD-FMK | |||||||||||
A14358 | Z-LEHD-FMK | |||||||||||
A14284 | Z-FA-FMK | |||||||||||
A15300 | Ivachtin | **** | ||||||||||
A15392 | Boc-D-FMK | |||||||||||
A14916 | Z-WEHD-FMK | |||||||||||
A15816 | Ac-DEVD-CHO | *** | * | **** | ** | ** | ** | *** | **** | ** |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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PETCM
Catalog No. A15308 -
Apoptosis Activator 2
Catalog No. A11944 Apoptosis ActivatorApoptosis Activator 2 强烈诱导caspase-3激活,PARP裂解和DNA片段化,导致细胞破坏(依赖Apaf-1),IC50为约4μM,对HMEC,PREC或MCF-10A细胞无效。 了解更多