Caspase

Inhibitory Selectivity

Catalog No.	Inhibitor Name	Pan-Caspase	Caspase-1	Caspase-2	Caspase-3	Caspase-4	Caspase-5	Caspase-6	Caspase-7	Caspase-8	Caspase-9
A10984	VX-765 (Belnacasan)		**			***
A12373	Z-VAD-FMK	*
A13503	Z-DEVD-FMK
A14915	Q-VD-OPh hydrate		****		****					***	***
A14919	Caspase-3/7 Inhibitor I				****				***
A12611	Z-VEID-FMK
A12637	Z-VDVAD-FMK
A12697	Z-DQMD-FMK
A12800	Z-IETD-FMK
A14358	Z-LEHD-FMK
A14284	Z-FA-FMK
A15300	Ivachtin				****
A15392	Boc-D-FMK
A14916	Z-WEHD-FMK
A15816	Ac-DEVD-CHO		***	*	****	**	**	**	***	****	**

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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Emricasan

Catalog No. A11394
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Caspase inhibitor

Emricasan is a first-in-class caspase inhibitor in clinical trials for the treatment of liver diseases. 了解更多

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Boc-D-FMK

Catalog No. A15392
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Caspase 抑制剂

BOC-D-FMK是Caspase-3的新型抑制剂。了解更多

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Z-VEID-FMK

Catalog No. A12611
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Caspase-6 抑制剂

Z-VEID-FMK是caspase-6 / Mch2的特异性识别序列。 Z-VEID-FMK是不可逆地抑制VEID依赖性胱天蛋白酶（例如caspase-6）活性的合成肽。抑制剂被设计为甲酯，以促进细胞渗透性。了解更多

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Z-VAD-FMK

Catalog No. A12373
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Pan Caspase 抑制剂

Z-VAD-FMK是一种细胞可渗透、不可逆的泛胱天蛋白酶抑制剂。体外抑制肿瘤细胞caspase加工和凋亡诱导(IC50 = 0.0015 - 5.8 mM)。活跃在体内。了解更多

Product Citations (30)

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