Caspase

Inhibitory Selectivity

Catalog No.	Inhibitor Name	Pan-Caspase	Caspase-1	Caspase-2	Caspase-3	Caspase-4	Caspase-5	Caspase-6	Caspase-7	Caspase-8	Caspase-9
A10984	VX-765 (Belnacasan)		**			***
A12373	Z-VAD-FMK	*
A13503	Z-DEVD-FMK
A14915	Q-VD-OPh hydrate		****		****					***	***
A14919	Caspase-3/7 Inhibitor I				****				***
A12611	Z-VEID-FMK
A12637	Z-VDVAD-FMK
A12697	Z-DQMD-FMK
A12800	Z-IETD-FMK
A14358	Z-LEHD-FMK
A14284	Z-FA-FMK
A15300	Ivachtin				****
A15392	Boc-D-FMK
A14916	Z-WEHD-FMK
A15816	Ac-DEVD-CHO		***	*	****	**	**	**	***	****	**

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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Apoptosis Activator 2

Catalog No. A11944
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Apoptosis Activator

Apoptosis Activator 2 强烈诱导caspase-3激活，PARP裂解和DNA片段化，导致细胞破坏（依赖Apaf-1），IC50为约4μM，对HMEC，PREC或MCF-10A细胞无效。了解更多

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