CB5083
目录号: A15827
p97 抑制剂
CB-5083 是一种新型的首创类、高效的口服可用 p97 抑制剂，它破坏细胞蛋白质稳态，并在实体瘤和血液病模型中显示出抗肿瘤活性。
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生物活性
| Discription | CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that disrupts cellular protein homeostasis and demonstrates anti-tumor activity in solid and hematological models . | |||||
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产品信息
| 目录号 | A15827 |
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| 分子式 | C24H23N5O2 |
| 分子量 | 413.4 |
| CAS号 | 1542705-92-9 |
| SMILES | CC1=CC2=C(C=CC=C2N1C3=NC4=C(COCC4)C(=N3)NCC5=CC=CC=C5)C(=O)N |
| 其他名称 | CB-5083, CB 5083 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 74 mg/mL (178.97 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 12 mg/mL (29.02 mM) | ||
| In vivo | 0.5% CMC Na+5% Tween 80 | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.19 mL | 120.95 mL | 241.9 mL |
| 0.5 mM | 4.84 mL | 24.19 mL | 48.38 mL |
| 1 mM | 2.42 mL | 12.09 mL | 24.19 mL |
| 5 mM | 0.48 mL | 2.42 mL | 4.84 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 CB5083 | CB5083 供应商 | CB5083 花费 | CB5083 生产商 | 订购 CB5083 | CB5083 代理商
| 购买 1542705-92-9 | 1542705-92-9 供应商 | 1542705-92-9 花费 | 1542705-92-9 生产商 | 订购 1542705-92-9 | 1542705-92-9 代理商