CBL-0137

Name: CBL-0137
SKU: A16836
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A16836

p53 activator / NF-κB 抑制剂

CBL0137（CBL-0137）在基于细胞的p53和NF-kB报告检测中，分别以EC50为0.37 μM和0.47 μM激活p53并抑制NF-kB。它还抑制组腺体伴侣FACT（促进染色质转录复合体）。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥525.00	现货
5mg	¥875.00	现货
10mg	¥1,470.00	现货
25mg	¥3,010.00	现货
50mg	¥4,095.00	现货
100mg	¥5,460.00	现货
*10mM 1mL in DMSO**	¥700.00	现货
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Data Sheet

SDS

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生物活性

Discription

CBL0137(CBL-0137) activates p53 and inhibits NF-kB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It also inhibits histone chaperone FACT (facilitates chromatin transcription complex).

Targets

Target	Value

产品信息

目录号	A16836
分子式	C21H24N2O2.HCl
分子量	372.89
CAS号	1197397-89-9
SMILES	CC(C)NCCN1C2=C(C=C(C=C2)C(=O)C)C3=C1C=CC(=C3)C(=O)C.Cl
其他名称	CBL0137, CBL 0137, Curaxin 137, Curaxin137, Curaxin-137, CBLC137, CBLC 137, CBLC-137
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	35 mg/mL (93.86 mM)
	Water	22 mg/mL (59 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.82 mL	134.09 mL	268.18 mL
0.5 mM	5.36 mL	26.82 mL	53.64 mL
1 mM	2.68 mL	13.41 mL	26.82 mL
5 mM	0.54 mL	2.68 mL	5.36 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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