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CC-223

目录号: A13078
mTOR 抑制剂
CC-223 是一种强效的 mTOR 激酶抑制剂(IC50=16 nM),对相关的脂质激酶 PI3K-alpha 的敏感性超过150倍(IC50=4μM)。
Grouped product items
规格 价格 库存 数量
1mg
¥210.00
现货
5mg
¥525.00
现货
10mg
¥840.00
现货
25mg
¥1,680.00
现货
50mg
¥2,835.00
现货
100mg
¥4,095.00
现货
10mM * 1mL in DMSO
¥560.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription CC-223 is a potent mTOR kinase inhibitor (IC50=16 nM), with >150-fold sensitivity over the related lipid kinase PI3K-alpha (IC50=4uM).
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A13078
分子式 C21H27N5O3
分子量 397.47
CAS号 1228013-30-6
SMILES CC(C)(C1=NC=C(C=C1)C2=CN=C3C(=N2)N(C(=O)CN3)C4CCC(CC4)OC)O
其他名称 CC 223, CC223
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 70 mg/mL (176.11 mM)
Water Insoluble
Ethanol 70 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.16 mL 125.8 mL 251.59 mL
0.5 mM 5.03 mL 25.16 mL 50.32 mL
1 mM 2.52 mL 12.58 mL 25.16 mL
5 mM 0.5 mL 2.52 mL 5.03 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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