CCR4 antagonist 2
目录号: A18471
CCR4 拮抗剂
CCR4 antagonist 2(化合物31)是一种新型的强效、口服生物利用度高的小分子CCR4拮抗剂,它能够抑制调节性T细胞(Treg)进入肿瘤微环境,而不抑制健康组织中的Treg数量。
Discription | CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. | |||||
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Cell Research |
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目录号 | A18471 |
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分子式 | C26H28Cl2N6O |
分子量 | 511.45 |
CAS号 | 2206788-99-8 |
SMILES | ClC(C=C(Cl)C=C1)=C1[C@@H](C)N2N=C(C#N)C3=C2N=C(C4=CC[C@H](N5[C@H](CO)CCC5)[C@H](C)C4)C=N3 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2