目录号: A10184
Aurora 抑制剂
CCT129202 是一种结构新颖的咪唑吡啶小分子抑制剂,代表性地抑制 Aurora激酶 活性。它对 Aurora激酶 显示出高度选择性,相较于测试的其他激酶群体,并在多种培养的人类肿瘤细胞系中抑制增殖。
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生物活性
Discription | CCT129202 is a representative of a structurally novel series of imidazopyridine small-molecule inhibitors of Aurora kinase activity. It shows high selectivity for the Aurora kinases over a panel of other kinases tested and inhibits proliferation in multiple cultured human tumor cell lines. |
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Cell Research |
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产品信息
目录号 | A10184 |
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分子式 | C23H25ClN8OS |
分子量 | 497 |
CAS号 | 942947-93-5 |
SMILES | CN(C)C1=CC=C(C=C1)C2=NC3=NC=C(C(=C3N2)N4CCN(CC4)CC(=O)NC5=NC=CS5)Cl |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
In vitro (25°C) | DMSO | 3 mg/mL (6.03 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 1% DMSO+30% polyethylene glycol+1% Tween 80 | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Preparing Stock Solutions
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.12 mL | 100.6 mL | 201.21 mL |
0.5 mM | 4.02 mL | 20.12 mL | 40.24 mL |
1 mM | 2.01 mL | 10.06 mL | 20.12 mL |
5 mM | 0.4 mL | 2.01 mL | 4.02 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 942947-93-5 | 942947-93-5 供应商 | 942947-93-5 花费 | 942947-93-5 生产商 | 订购 942947-93-5 | 942947-93-5 代理商