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CCT129202

目录号: A10184
Aurora 抑制剂
CCT129202 是一种结构新颖的咪唑吡啶小分子抑制剂,代表性地抑制 Aurora激酶 活性。它对 Aurora激酶 显示出高度选择性,相较于测试的其他激酶群体,并在多种培养的人类肿瘤细胞系中抑制增殖。
Grouped product items
规格 价格 库存 数量
1mg
¥210.00
现货
2mg
¥315.00
现货
5mg
¥525.00
现货
10mg
¥1,015.00
现货
25mg
¥1,820.00
现货
50mg
¥2,940.00
现货
100mg
¥4,340.00
现货
500mg
¥9,415.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription

CCT129202 is a representative of a structurally novel series of imidazopyridine small-molecule inhibitors of Aurora kinase activity. It shows high selectivity for the Aurora kinases over a panel of other kinases tested and inhibits proliferation in multiple cultured human tumor cell lines.

Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A10184
分子式 C23H25ClN8OS
分子量 497
CAS号 942947-93-5
SMILES CN(C)C1=CC=C(C=C1)C2=NC3=NC=C(C(=C3N2)N4CCN(CC4)CC(=O)NC5=NC=CS5)Cl
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro (25°C) DMSO 3 mg/mL (6.03 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.12 mL 100.6 mL 201.21 mL
0.5 mM 4.02 mL 20.12 mL 40.24 mL
1 mM 2.01 mL 10.06 mL 20.12 mL
5 mM 0.4 mL 2.01 mL 4.02 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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