CCT245737

Name: CCT245737
SKU: A17239
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A17239

CHK1 抑制剂

CCT245737 是一种强效、选择性且可口服的检查点激酶1 (CHK1) 抑制剂。CCT245737 表现出 CHK1 IC50 = 1.3 nM，CHK2 IC50 = 2440 nM，G2 检查点废止 IC50 = 30 nM。小鼠口服生物利用度 F (oral) = 100%。

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥490.00	现货
10mg	¥805.00	现货
25mg	¥1,610.00	现货
50mg	¥2,660.00	现货
100mg	¥4,025.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
更大包装	更多折扣

大包装询价

Notify me when the price drops

全国免运费, 顺丰次日达

重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

生物活性

Discription

CCT245737 is a potent, selective and orally active checkpoint kinase 1 (CHK1) inhibitor. CCT245737 showed CHK1 IC50 = 1.3 nM, CHK2 IC50 = 2440 nM, G2 check point abrogation IC50 = 30 nM. Mouse F (oral)=100%.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A17239
分子式	C16H16F3N7O
分子量	379.3472
CAS号	1489389-18-5
SMILES	N#CC1=NC=C(NC2=NC=C(C(F)(F)F)C(NC[C@H]3CNCCO3)=C2)N=C1
其他名称	CCT 245737; CCT-245737
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 72 mg/mL (189.8 mM)
	Water	Insoluble
	Ethanol	Warmed: 9 mg/mL (23.72 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.36 mL	131.81 mL	263.61 mL
0.5 mM	5.27 mL	26.36 mL	52.72 mL
1 mM	2.64 mL	13.18 mL	26.36 mL
5 mM	0.53 mL	2.64 mL	5.27 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords: 购买 CCT245737 | CCT245737 供应商 | CCT245737 花费 | CCT245737 生产商 | 订购 CCT245737 | CCT245737 代理商 | 购买 1489389-18-5 | 1489389-18-5 供应商 | 1489389-18-5 花费 | 1489389-18-5 生产商 | 订购 1489389-18-5 | 1489389-18-5 代理商