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Celastrol

目录号: A10192
Celastrol 是一种从中国的雷公藤(T. wilfordii)中提取的三萜类抗氧化化合物。在一项关于大鼠肝脏脂质过氧化的独立实验中,celastrol 的 IC50 值为 7 微摩尔,其抗氧化能力约为 α-生育酚 的 15 倍。
Grouped product items
规格 价格 库存 数量
5mg
¥280.00
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10mg
¥315.00
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25mg
¥595.00
现货
50mg
¥840.00
现货
100mg
¥1,155.00
现货
10mM * 1mL in DMSO
¥350.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Celastrol发表的3篇文献
  • Xuechun Wang, .et al. , Int J Mol Sci, 2023, Mar 8;24(6):5204 PMID: 36982279
  • R. San Gil, .et al. , bioRxiv, 2020, Jan
  • Abdin AA, .et al. , Eur J Pharmacol., 2014, 742:102-12 PMID: 25218987
  • 生物活性
    Discription

    Celastrol is a triterpenoid antioxidant compound isolated from the Chinese Thunder of God vine (T. wilfordii). In an isolated rat liver assay of lipid peroxidation, celastrol had an IC50 value of 7 µM, equivalent to about 15 times the antioxidant potency of α-tocopherol.

    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A10192
    分子式 C29H38O4
    分子量 450.6
    CAS号 34157-83-0
    SMILES CC1=C(C(=O)C=C2C1=CC=C3[C@]2(CC[C@@]4([C@@]3(CC[C@@]5([C@H]4C[C@](CC5)(C)C(=O)O)C)C)C)C)O
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 82 mg/mL (181.97 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.19 mL 110.96 mL 221.93 mL
    0.5 mM 4.44 mL 22.19 mL 44.39 mL
    1 mM 2.22 mL 11.1 mL 22.19 mL
    5 mM 0.44 mL 2.22 mL 4.44 mL
    Useful Calculator

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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