目录号: A10193
COX-2 抑制剂
Celecoxib 是一种含硫非甾体抗炎药(NSAID)和选择性 COX-2 抑制剂,用于治疗骨关节炎、风湿性关节炎、急性疼痛、痛经和月经症状,以及在家族性腺瘤性息肉病患者中减少结肠和直肠息肉的数量。
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生物活性
Discription | Celecoxib is a sulfa non-steroidal anti-inflammatory drug (NSAID) and selective COX-2 inhibitor used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. |
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Cell Research |
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产品信息
目录号 | A10193 |
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分子式 | C17H14F3N3O2S |
分子量 | 381.4 |
CAS号 | 169590-42-5 |
SMILES | CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F |
其他名称 | Celebrex, Celebra |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
In vitro (25°C) | DMSO | 65 mg/mL (170.44 mM) | |
Water | Insoluble | ||
Ethanol | 28 mg/mL (73.42 mM) | ||
In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Preparing Stock Solutions
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 26.22 mL | 131.1 mL | 262.19 mL |
0.5 mM | 5.24 mL | 26.22 mL | 52.44 mL |
1 mM | 2.62 mL | 13.11 mL | 26.22 mL |
5 mM | 0.52 mL | 2.62 mL | 5.24 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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