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WEE1 Inhibitor
MK-1775 是一种在体外和体内都具有强效和选择性的 Wee1激酶抑制剂。- Hayden L Bell, .et al. , Cancer Cell Int, 2023, Sep 15;23(1):202 PMID: 37715172
- Chiao-Ping Chen, .et al. , Biomed Pharmacother, 2023, Oct:166:115389 PMID: 37659202
- Ting-Yu Chang, .et al. , Biomed Pharmacother, 2021, Jun;138:111485 PMID: 33740521
- 2018, .et al. , FEBS Open Bio, 2018, Jun; 8(6): 1001-1012 PMID: 29928579
- Rulina AV, .et al. , Cell Death Dis, 2016, Dec 1;7(12):e2505 PMID: 27906189
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Wee1/Chk inhibitor
PD0166285 是一种强效的 Wee1 和 Chk1 抑制剂，具有纳摩尔浓度的活性。PD0166285 是一种新型的 G2 checkpoint 破坏剂。- Trang H. Nguyen Vu, .et al. , Cancer Sci, 2023, Dec; 114(12): 4664-4676 PMID: 37724648
