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￥ 0.00 Cell Metabolism
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Dyphylline
Catalog No. A10339 Adenosine receptor 拮抗剂Dyphylline是黄嘌呤衍生物，具有支气管扩张药和血管扩张药的作用。 它充当腺苷受体拮抗剂和磷酸二酯酶抑制剂。 了解更多 -
Milrinone (Primacor)
Catalog No. A10592 PDE3 抑制剂Milrinone (Primacor)是一种有效的选择性磷酸二酯酶3抑制剂，IC50为0.42μM，可抑制FIII PDE。 了解更多 -
Zardaverine
Catalog No. A12550 -
Avanafil
Catalog No. A12619 -
Crisaborole (AN2728)
Catalog No. A12776 PDE4 抑制剂?AN2728是一种局部给药的含硼抗炎化合物，可抑制PDE4活性，从而抑制TNFalpha，IL-12，IL-23和其他细胞因子的释放。抑制PDE4的 IC50 值为0.49 μM。 了解更多 -
PF-04447943
Catalog No. A13121 -
Deltarasin HCl
Catalog No. A13722 -
HA130
Catalog No. A15546 -
Sildenafil Mesylate
Catalog No. A16142 -
Vesnarinone
Catalog No. A13313 -
Roflumilast N-oxide
Catalog No. A16984 -
Ademetionine
Catalog No. A17531 PDE4B inhibitorAdemetionine, also known as AdoMet; MSI-195; SAMe, S-adenosylmethionine, is a PDE4B inhibitor potentially for treatment of primary biliary cirrhosis and major depressive disorder. 了解更多 -
Fosphenytoin disodium
Catalog No. A18184 PDE3 inhibitorFosphenytoin Sodium is the sodium salt form of fosphenytoin, a prodrug that is hydrolyzed to the anticonvulsant phenytoin. It is an PDE3 (phosphodiesterase 3) inhibitor. 了解更多 -
PDE12-IN-3
Catalog No. A18579 PDE12 inhibitorPDE12-IN-3 is a phosphodiesterase 12 (PDE12) inhibitor with a pXC50 of 7.68. Antiviral activity. 了解更多 -
VP3.15
Catalog No. A18538 dual PDE7/GSK-3 inhibitorVP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS). 了解更多 -
PF-05085727
Catalog No. A20098 PDE2A inhibitorPF-05085727 is a potent, selective and brain penetrant Phosphodiesterase 2A (PDE2A) inhibitor with an IC50 of 2 nM. 了解更多 -
HSP27 inhibitor J2
Catalog No. A18874 HSP27 inhibitorHSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. 了解更多 -
Retaspimycin
Catalog No. A15221 Hsp90 inhibitorRetaspimycin is a potent and water-soluble inhibitor of Hsp90, with EC50s of 119 nM for both Hsp90 and Grp9. 了解更多 -
Apoptozole
Catalog No. A21177 Hsc70 and Hsp70 inhibitorApoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, with Kds of 0.21 and 0.14?μM, respectively, and can induce apoptosis. 了解更多 -
SNX-5422 Mesylate
Catalog No. A21512 Hsp90 inhibitorSNX-5422 Mesylate (PF-04929113 Mesylate), a prodrug of SNX-2112, is an orally active Hsp90 inhibitor, with a Kd of 41 nM, and also induces Her-2 degradation, with an IC50 of 37?nM. 了解更多 -
HSP70-IN-1
Catalog No. A21716 HSP inhibitorHSP70-IN-1 is a heat shock protein (HSP) inhibitor; inhibits the growth of Kasumi-1 cells with an IC50 of 2.3 μM. 了解更多 -
Arimoclomol maleate
Catalog No. A21912 co-inducer of heat shock proteins (HSP)Arimoclomol maleate (BRX-220) is a co-inducer of heat shock proteins (HSP). 了解更多 -
17-AAG (KOS953)
Catalog No. A10010 HSP90 抑制剂17-AAG (KOS953)是一种有效的HSP90抑制剂，无细胞试验中IC50为5 nM，作用于来自肿瘤细胞的HSP90比作用于来自正常细胞HSP90结合亲和力高100倍。 了解更多 -
AUY922 (Luminespib, NVP-AUY922)
Catalog No. A10659 HSP90 抑制剂AUY922 (Luminespib,NVP-AUY922)是一种高效的HSP90抑制剂，在Hsp90 FP结合测定中的IC50 = 21 nM，并在体外抑制多种人类癌细胞系的增殖，GI50平均为9 nM。Luminespib (AUY-922, NVP-AUY922)是一种高效的HSP90抑制剂，无细胞试验中作用于HSP90α/β的IC50为13 nM /21 nM，对HSP90家族成员GRP94和TRAP-1具有稍弱的作用，与任何小分子HSP90配体均可紧密结合。 了解更多 -
NVP-BEP800
Catalog No. A10660 HSP90 抑制剂NVP-BEP800是一种新型的，完全合成的，口服可生物利用的抑制剂，可与Hsp90的NH2末端ATP结合袋结合。 了解更多 -
Onalespib (AT13387)
Catalog No. A11062 HSP90 抑制剂Onalespib (AT13387)是Hsp90的靶向抑制剂，可抑制其伴侣功能并促进涉及肿瘤细胞增殖和存活的致癌信号蛋白的降解。 了解更多 -
PF-04929113 (SNX-5422)
Catalog No. A11074 Hsp90 抑制剂PF-04929113 (SNX-5422)是一种有效的，选择性的HSP90抑制剂，Kd为41 nM，且诱导Her-2降解，IC50为37 nM。 了解更多 -
Ganetespib (STA-9090)
Catalog No. A11402 Hsp90 抑制剂Ganetespib (STA-9090)是Hsp90的有效合成小分子抑制剂，Hsp90是一种伴侣蛋白，对于某些其他蛋白的功能至关重要，这些蛋白可驱动许多不同类型的癌症的生长，增殖和存活。 了解更多 -
17-DMAG HCl (Alvespimycin)
Catalog No. A10011 Hsp90 抑制剂17-DMAG HCl (Alvespimycin)是17-AAG和格尔德霉素的水溶性类似物，与Hsp90的ATP结合位点结合并抑制其伴侣活性。显示出比17-AAG更有效的抗肿瘤活性。 了解更多 -
KW-2478
Catalog No. A11195
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