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CEP-18770 (Delanzomib)

CEP-18770 (Delanzomib)

Name: CEP-18770 (Delanzomib)
SKU: A11145

目录号: A11145

Proteasome 抑制剂

CEP-18770 (Delanzomib) Chemical Structure

CAS NO. 847499-27-8

CEP-18770 (Delanzomib)是一种新型口服活性蛋白酶体抑制剂，IC50为3.8 nM，具有良好的肿瘤选择性，可用于治疗对蛋白酶体抑制有反应的MM和其他恶性肿瘤。

库存：现货 Shipped in 7-10 Days

规格	价格	数量
5 mg	￥ 490.00
10 mg	￥ 840.00
50 mg	￥ 2,450.00
100 mg	￥ 4,200.00
10mM * 1mL in DMSO	￥ 819.00

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生物活性

CEP-18770 (Delanzomib)是一种新型口服活性蛋白酶体抑制剂，IC50为3.8 nM，具有良好的肿瘤选择性，可用于治疗对蛋白酶体抑制有反应的MM和其他恶性肿瘤。

靶点信息

Chymotrypsin-like proteasome
3.8 nM

溶解度 *

In vitro	DMSO	73 mg/mL (176.63 mM)
	Water	Insoluble
	Ethanol	73 mg/mL (176.63 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.2 mL	120.98 mL	241.95 mL
0.5 mM	4.84 mL	24.2 mL	48.39 mL
1 mM	2.42 mL	12.1 mL	24.2 mL
5 mM	0.48 mL	2.42 mL	4.84 mL

*The above data is based on the productmolecular weight 413.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11145
作用机制	Inhibitor (抑制剂)
M. Wt	413.3
Formula	C21H28BN3O5
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	847499-27-8
Synonyms	CEP18770
SMILES	B([C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)C1=CC=CC(=N1)C2=CC=CC=C2)(O)O