CEP-40783
目录号: A20331
AXL/c-Met inhibitor
CEP-40783 是一种效力强大、选择性高且可口服的 AXL 和 c-Met 抑制剂,其 IC50 值分别为 7 nM 和 12 nM。
Discription | CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively. |
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目录号 | A20331 |
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分子式 | C31H26F2N4O6 |
分子量 | 588.56 |
CAS号 | 1437321-24-8 |
SMILES | O=C(C1=CN(C(C)C)C(N(C2=CC=C(F)C=C2)C1=O)=O)NC3=CC=C(OC4=CC=NC5=CC(OC)=C(OC)C=C45)C(F)=C3 |
其他名称 | CEP 40783, CEP40783; RXDX-106, RXDX106, RXDX 106 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 9 mg/mL (15.29 mM) | |
Water | Insoluble | ||
Ethanol | 2 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 16.99 mL | 84.95 mL | 169.91 mL |
0.5 mM | 3.4 mL | 16.99 mL | 33.98 mL |
1 mM | 1.7 mL | 8.5 mL | 16.99 mL |
5 mM | 0.34 mL | 1.7 mL | 3.4 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2