Cevipabulin (TTI-237)

Name: Cevipabulin (TTI-237)
SKU: A12591
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A12591

1 篇发表文献

Cevipabulin（TTI-237），一种抗微管药物，是一种具有潜在抗肿瘤活性的小型合成三唑并嘧啶衍生物分子。TTI-237具有与其他长春碱类化合物不同的新型作用机制，它特异性地结合于微管蛋白的长春碱结合位点，并促进微管蛋白向微管的聚合。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥315.00	现货
10mg	¥595.00	现货
25mg	¥1,225.00	现货
50mg	¥2,205.00	现货
100mg	¥4,200.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of Cevipabulin (TTI-237)

Cevipabulin fumarate

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Cevipabulin (TTI-237)发表的1篇文献

Yao-Yu Hsieh, .et al. , Mol Oncol, 2023, Oct 16 PMID: 37842807

生物活性

Discription	Cevipabulin (TTI-237), an antimicrotubule agent, is a small synthetic molecule of triazolopyrimidine derivative with potential antitumor activity. With a novel mechanism of action distinct from the action of other vinca alkaloid compounds, TTI-237 specifically binds to tubulin at the vinca site, and promotes the polymerization of tubulin into microtubules.

产品信息

目录号	A12591
分子式	C18H18ClF5N6O
分子量	464.82
CAS号	849550-05-6
SMILES	C[C@@H](C(F)(F)F)NC1=C(C(=NC2=NC=NN12)Cl)C3=C(C=C(C=C3F)OCCCNC)F
其他名称	TTI237, D06576
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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