CG-806
目录号: A19814
FLT3/BTK inhibitor
CG-806 是一种口服活性、高效、非共价 pan-FLT3/pan-BTK 抑制剂,对 FLT3 的 IC50 为 0.08 μM。CG-806 对 FLT3 野生型 (WT) 转染的 Ba/F3 细胞的 IC50 为 11 nM。
Discription | CG-806 is an orally active, potent and non-covalent pan-FLT3/pan-BTK inhibitor with an IC50 of 0.08 μM for FLT3. CG-806 has an IC50 of 11 nM against FLT3 wild type (WT)-transfected Ba/F3 cells. |
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目录号 | A19814 |
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分子式 | C26H19F4N5O2 |
分子量 | 509.45 |
CAS号 | 1370466-81-1 |
SMILES | O=C(NC1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(C3=CC=C(C4=NC=C(C)N4)C5=C3CNC5=O)C(F)=C2 |
其他名称 | CG 806; CG806; CG-026806; CG 026806; CG026806 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2