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CGP-52411是表皮生长因子受体（EGFR）的选择性抑制剂（体外IC50 = 0.3μM）。还抑制和逆转与阿尔茨海默氏病有关的Aβ42纤维的形成。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.36 mL | 151.81 mL | 303.63 mL |
| 0.5 mM | 6.07 mL | 30.36 mL | 60.73 mL |
| 1 mM | 3.04 mL | 15.18 mL | 30.36 mL |
| 5 mM | 0.61 mL | 3.04 mL | 6.07 mL |
*The above data is based on the productmolecular weight 329.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12867 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 329.35 |
| Formula | C20H15N3O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 145915-58-8 |
| Synonyms | CGP 52411, CGP52411 |
| SMILES | C1=CC=C(C=C1)NC2=C(C=C3C(=C2)C(=O)NC3=O)NC4=CC=CC=C4 |
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