CH5132799
目录号: A11169
PI3K 抑制剂
CH5132799 是一种新型的 I 类 PI3K 抑制剂，特别是对 PI3Kα 表现出强烈的抑制活性（IC(50)=0.014 μM）。
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生物活性
| Discription | CH5132799 is a novel class I PI3K inhibitor, which exhibited a strong inhibitory activity especially against PI3Kα (IC(50)=0.014 μM). |
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产品信息
| 目录号 | A11169 |
|---|---|
| 分子式 | C15H19N7O3S |
| 分子量 | 377.42 |
| CAS号 | 1007207-67-1 |
| SMILES | CS(=O)(=O)N1CCC2=C(N=C(N=C21)N3CCOCC3)C4=CN=C(N=C4)N |
| 其他名称 | CH-5132799 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 12 mg/mL (31.79 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 1% DMSO+30% polyethylene glycol+1% Tween 80 | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.5 mL | 132.48 mL | 264.96 mL |
| 0.5 mM | 5.3 mL | 26.5 mL | 52.99 mL |
| 1 mM | 2.65 mL | 13.25 mL | 26.5 mL |
| 5 mM | 0.53 mL | 2.65 mL | 5.3 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1007207-67-1 | 1007207-67-1 供应商 | 1007207-67-1 花费 | 1007207-67-1 生产商 | 订购 1007207-67-1 | 1007207-67-1 代理商