Chaetocin
Chaetocin 是一种组蛋白甲基转移酶 SUV39H1 抑制剂（IC50 = 0.8 μM）。在体外能诱导多发性骨髓瘤细胞系发生凋亡；在体内小鼠多发性骨髓瘤模型中表现出抗增殖活性。
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生物活性
| Discription | Chaetocin is a histone methyltransferase SUV39H1 inhibitor (IC50 = 0.8 μM). Induces apoptosis in myeloma cell lines in vitro; exhibits antiproliferative activity in a mouse myeloma model in vivo. | ||
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产品信息
| 目录号 | A12812 |
|---|---|
| 分子式 | C30H28N6O6S4 |
| 分子量 | 696.84 |
| CAS号 | 28097-03-2 |
| SMILES | CN1C(=O)C23CC4(C(N2C(=O)C1(SS3)CO)NC5=CC=CC=C54)C67CC89C(=O)N(C(C(=O)N8C6NC1=CC=CC=C71)(SS9)CO)C |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | Warmed: 87 mg/mL (124.85 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.35 mL | 71.75 mL | 143.5 mL |
| 0.5 mM | 2.87 mL | 14.35 mL | 28.7 mL |
| 1 mM | 1.44 mL | 7.18 mL | 14.35 mL |
| 5 mM | 0.29 mL | 1.44 mL | 2.87 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 28097-03-2 | 28097-03-2 供应商 | 28097-03-2 花费 | 28097-03-2 生产商 | 订购 28097-03-2 | 28097-03-2 代理商