Chaetocin

Name: Chaetocin
SKU: A12812

目录号: A12812

SUV39H HMT 抑制剂

Chaetocin Chemical Structure

CAS NO. 28097-03-2

Chaetocin是组蛋白甲基转移酶SUV39H1抑制剂（IC50 = 0.8μM）。在体外诱导骨髓瘤细胞系的凋亡；在小鼠骨髓瘤模型中具有抗增殖活性。

库存：现货

规格	价格	数量
1 mg	￥ 595.00
2 mg	￥ 1,050.00
5 mg	￥ 2,100.00
10 mg	￥ 3,500.00

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生物活性

Chaetocin是组蛋白甲基转移酶SUV39H1抑制剂（IC50 = 0.8μM）。在体外诱导骨髓瘤细胞系的凋亡；在小鼠骨髓瘤模型中具有抗增殖活性。

靶点信息

dSU(VAR)3-9	mouse G9a	Neurospora crassa DIM5
0.8 μM	2.5 μM	3 μM

溶解度 *

In vitro	DMSO	Warmed: 87 mg/mL (124.85 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.35 mL	71.75 mL	143.5 mL
0.5 mM	2.87 mL	14.35 mL	28.7 mL
1 mM	1.44 mL	7.18 mL	14.35 mL
5 mM	0.29 mL	1.44 mL	2.87 mL

*The above data is based on the productmolecular weight 696.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12812
作用机制	Inhibitor (抑制剂)
M. Wt	696.84
Formula	C30H28N6O6S4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	28097-03-2
SMILES	CN1C(=O)C23CC4(C(N2C(=O)C1(SS3)CO)NC5=CC=CC=C54)C67CC89C(=O)N(C(C(=O)N8C6NC1=CC=CC=C71)(SS9)CO)C