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Chelerythrine Chloride是一种有效的，选择性的PKC拮抗剂， IC50为0.66 μM。影响PKC从细胞质到质膜的转运。显示可防止神经突生长。以浓度和时间表依赖性方式诱导凋亡。
| In vitro | DMSO | 3 mg/mL (7.79 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.06 mL | 130.28 mL | 260.55 mL |
| 0.5 mM | 5.21 mL | 26.06 mL | 52.11 mL |
| 1 mM | 2.61 mL | 13.03 mL | 26.06 mL |
| 5 mM | 0.52 mL | 2.61 mL | 5.21 mL |
*The above data is based on the productmolecular weight 383.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10196 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 383.8 |
| Formula | C21H18ClNO4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 3895-92-9 |
| SMILES | C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5.[Cl-] |
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