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CHIR-99021 trihydrochloride (CT99021 trihydrochloride) is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.4 mL | 87 mL | 174 mL |
| 0.5 mM | 3.48 mL | 17.4 mL | 34.8 mL |
| 1 mM | 1.74 mL | 8.7 mL | 17.4 mL |
| 5 mM | 0.35 mL | 1.74 mL | 3.48 mL |
*The above data is based on the productmolecular weight 574.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21436 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 574.72 |
| Formula | C22H21Cl5N8 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1782235-14-6 |
| Synonyms | CT99021 trihydrochloride, CT 99021, CT 99021, CHIR99021, CHIR 99021 |
| SMILES | N#CC1=CC=C(NCCNC2=NC=C(C3=NC=C(C)N3)C(C4=CC=C(Cl)C=C4Cl)=N2)N=C1.[H]Cl.[H]Cl.[H]Cl |
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