CHMFL-EGFR-202

Name: CHMFL-EGFR-202
SKU: A12524
Price: 770 CNY
Rating: 5 (288 reviews)

目录号: A12524

EGFR 抑制剂

CHMFL-EGFR-202 是一种强效的、不可逆的表皮生长因子受体（EGFR）突变激酶抑制剂，对耐药突变 EGFR T790M 和野生型 EGFR 激酶的半抑制浓度（IC50）分别为 5.3 nM 和 8.3 nM。

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Grouped product items
规格	价格	库存
1mg	¥770.00	现货
2mg	¥1,190.00	现货
5mg	¥1,820.00	现货
10mg	¥2,730.00	现货
25mg	¥4,095.00	现货
50mg	¥5,740.00	现货
100mg	¥7,875.00	现货
*10mM 1mL in DMSO**	¥2,205.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

CHMFL-EGFR-202 is a potent, irreversible inhibitor of epidermal growth factor receptor (EGFR) mutant kinase, with IC50s of 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12524
分子式	C25H24ClN7O2
分子量	489.96
CAS号	2089381-40-6
SMILES	O=C(N(C1)CCC[C@H]1N2C3=NC=NC(N)=C3C(C4=CC(Cl)=C(OCC5=NC=CC=C5)C=C4)=N2)C=C
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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